Paleoclimate

Earth's Variable Climatic Past

Jesse Smith and Julia Uppenbrink
Science 27 April 2001: 657.
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News

Myriad Ways to Reconstruct Past Climate

Erik Stokstad
Science 27 April 2001: 658-659.
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The Tropics Return to the Climate System

Richard A. Kerr
Science 27 April 2001: 660-661.
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Reviews

The Evolution of Climate Over the Last Millennium

P. D. Jones, T. J. Osborn, and K. R. Briffa
Science 27 April 2001: 662-667.
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Cultural Responses to Climate Change During the Late Holocene

Peter B. deMenocal
Science 27 April 2001: 667-673.
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Range Shifts and Adaptive Responses to Quaternary Climate Change

Margaret B. Davis and Ruth G. Shaw
Science 27 April 2001: 673-679.
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Sea Level Change Through the Last Glacial Cycle

Kurt Lambeck and John Chappell
Science 27 April 2001: 679-686.
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Trends, Rhythms, and Aberrations in Global Climate 65 Ma to Present

James Zachos, Mark Pagani, Lisa Sloan, Ellen Thomas, and Katharina Billups
Science 27 April 2001: 686-693.
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This Week in Science

Editor summaries of this week's papers.
Science 27 April 2001: 597.
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Editorial:
Disappearing Stem Cells, Disappearing Science

Irving L. Weissman and David Baltimore
Science 27 April 2001: 601.
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Editors' Choice

Highlights of the recent literature.
Science 27 April 2001: 603.
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NetWatch

Best of the Web in science.
Science 27 April 2001: 607.
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 NEW PRODUCTS

Science 27 April 2001: 749-750.

 AAAS News & Notes

Science 27 April 2001: 751-752.

News of the Week

DRUG PATENTS:
Universities, NIH Hear the Price Isn't Right on Essential Drugs

Eliot Marshall
Science 27 April 2001: 614-615.
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AIDS ORIGINS:
Disputed AIDS Theory Dies Its Final Death

Jon Cohen
Science 27 April 2001: 615.
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DEVELOPMENTAL BIOLOGY:
Stem Cells Are Coaxed to Produce Insulin

Gretchen Vogel
Science 27 April 2001: 615-617.
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ASTROPHYSICS:
Images and Model Catch Planets As They Form

Mark Muro
Science 27 April 2001: 618.
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ASTRONOMY:
Critics of 'Halo Matter' Outrace the Presses

Mark Sincell
Science 27 April 2001: 618-619.
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MIDDLE EAST:
Two Pledges Boost SESAME Project

Robert Koenig
Science 27 April 2001: 619-620.
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JAPAN:
Reforms Could Threaten Facility Spending Hike

Dennis Normile
Science 27 April 2001: 620.
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TASTE RESEARCH:
New Gene May Be Key to Sweet Tooth

R. John Davenport
Science 27 April 2001: 620.
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ARCHAEOLOGY:
The First Urban Center in the Americas

Heather Pringle
Science 27 April 2001: 621.
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NEUROSCIENCE:
How the Brain Understands Music

Constance Holden
Science 27 April 2001: 623.
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ScienceScope

Science 27 April 2001: 617.
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Random Samples

Science 27 April 2001: 635.
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News Focus

The Mitochondrion: Is It Central to Apoptosis?

Elizabeth Finkel
Science 27 April 2001: 624-626.
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AMERICAN ASSOCIATION OF PHYSICAL ANTHROPOLOGISTS MEETING:
Studying Humans--and Their Cousins and Parasites

Ann Gibbons
Science 27 April 2001: 627-629.
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GERMAN RESEARCH MINISTER:
Bulmahn Is Bullish on Science Reforms

Robert Koenig and Gretchen Vogel
Science 27 April 2001: 629-630.
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ARCHAEOLOGY:
New Trips Through the Back Alleys of Agriculture

Kathryn Brown
Science 27 April 2001: 631-633.
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Letters

This Week's Letters

Science 27 April 2001: 637.
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 GM Crops and Patterns of Pesticide Use

Janet Carpenter;, L. LaReesa Wolfenbarger, and Paul R. Phifer
Science 27 April 2001: 637-638.
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 Risk Assessment Data for GM Crops

Peter Gregory, Klaus von Grebmer, Orlo Ehart;, L. LaReesa Wolfenbarger, and Paul R. Phifer
Science 27 April 2001: 638-639.
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 Conflicts of Interest

David Korn
Science 27 April 2001: 639.
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 Human Cloning--Not If, but When

Geeta Chougule; and Charlie Murtaugh
Science 27 April 2001: 639.
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 CORRECTIONS AND CLARIFICATIONS

Science 27 April 2001: 639.
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Books et al.

VOLCANOLOGY:
Not "A Piece of Cake"!

Haraldur Sigurdsson
Science 27 April 2001: 643-644.
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CLIMATE AND HISTORY:
The Shadow of Droughts' Deaths

Vaclav Smil
Science 27 April 2001: 644-645.
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ASTRONOMY:
More Than a Mass of Incandescent Gas

J. R. Jokipii
Science 27 April 2001: 645.
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 Books Received

Science 27 April 2001: 645.

Policy Forum

ENVIRONMENT AND DEVELOPMENT:
Sustainability Science

Robert W. Kates, William C. Clark, Robert Corell, J. Michael Hall, Carlo C. Jaeger, Ian Lowe, James J. McCarthy, Hans Joachim Schellnhuber, Bert Bolin, Nancy M. Dickson, Sylvie Faucheux, Gilberto C. Gallopin, Arnulf Grübler, Brian Huntley, Jill Jäger, Narpat S. Jodha, Roger E. Kasperson, Akin Mabogunje, Pamela Matson, Harold Mooney, Berrien Moore III, Timothy O'Riordan, and Uno Svedlin
Science 27 April 2001: 641-642.
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Perspectives

MICROBIOLOGY:
Enhanced: Fighting Anthrax with a Mutant Toxin

Sjur Olsnes and Jørgen Wesche
Science 27 April 2001: 647-648.
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LASER CHEMISTRY:
Keeping Reactions Under Quantum Control

Sean M. Hurley and A. Welford Castleman Jr.
Science 27 April 2001: 648-649.
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NANOTUBES:
Burn and Interrogate

Mildred S. Dresselhaus
Science 27 April 2001: 650-651.
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BIOINORGANIC CHEMISTRY:
Oxygenase Pathways: Oxo, Peroxo, and Superoxo

Lawrence Que Jr. and Yoshihito Watanabe
Science 27 April 2001: 651-653.
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RNA STRUCTURE:
Pulling on Hair(pins)

J. M. Fernandez, S. Chu, and A. F. Oberhauser
Science 27 April 2001: 653-654.
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Research Articles

Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax

Bret R. Sellman, Michael Mourez, and R. John Collier
Science 27 April 2001: 695-697.
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Direct Detection of Galactic Halo Dark Matter

B. R. Oppenheimer, N. C. Hambly, A. P. Digby, S. T. Hodgkin, and D. Saumon
Science 27 April 2001: 698-702.
Published online 22 March 2001 [DOI: 10.1126/science.1059954] (in Science Express Research Articles)
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Reports

Energy Gaps in "Metallic" Single-Walled Carbon Nanotubes

Min Ouyang, Jin-Lin Huang, Chin Li Cheung, and Charles M. Lieber
Science 27 April 2001: 702-705.
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Engineering Carbon Nanotubes and Nanotube Circuits Using Electrical Breakdown

Philip G. Collins, Michael S. Arnold, and Phaedon Avouris
Science 27 April 2001: 706-709.
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Selective Bond Dissociation and Rearrangement with Optimally Tailored, Strong-Field Laser Pulses

Robert J. Levis, Getahun M. Menkir, and Herschel Rabitz
Science 27 April 2001: 709-713.
Published online 29 March 2001 [DOI: 10.1126/science.1059133] (in Science Express Reports)
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A Complex Pattern of Mantle Flow in the Lau Backarc

Gideon P. Smith, Douglas A. Wiens, Karen M. Fischer, Leroy M. Dorman, Spahr C. Webb, and John A. Hildebrand
Science 27 April 2001: 713-716.
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Detection of Widespread Fluids in the Tibetan Crust by Magnetotelluric Studies

Wenbo Wei, Martyn Unsworth, Alan Jones, John Booker, Handong Tan, Doug Nelson, Leshou Chen, Shenghui Li, Kurt Solon, Paul Bedrosian, Sheng Jin, Ming Deng, Juanjo Ledo, David Kay, and Brian Roberts
Science 27 April 2001: 716-719.
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Observations of Ozone Formation in Power Plant Plumes and Implications for Ozone Control Strategies

T. B. Ryerson, M. Trainer, J. S. Holloway, D. D. Parrish, L. G. Huey, D. T. Sueper, G. J. Frost, S. G. Donnelly, S. Schauffler, E. L. Atlas, W. C. Kuster, P. D. Goldan, G. Hübler, J. F. Meagher, and F. C. Fehsenfeld
Science 27 April 2001: 719-723.
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Dating Caral, a Preceramic Site in the Supe Valley on the Central Coast of Peru

Ruth Shady Solis, Jonathan Haas, and Winifred Creamer
Science 27 April 2001: 723-726.
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Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei-Xing Zong, Emily H.-Y. Cheng, Tullia Lindsten, Vily Panoutsakopoulou, Andrea J. Ross, Kevin A. Roth, Grant R. MacGregor, Craig B. Thompson, and Stanley J. Korsmeyer
Science 27 April 2001: 727-730.
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Allosteric Control of RNA Polymerase by a Site That Contacts Nascent RNA Hairpins

Innokenti Toulokhonov, Irina Artsimovitch, and Robert Landick
Science 27 April 2001: 730-733.
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Reversible Unfolding of Single RNA Molecules by Mechanical Force

Jan Liphardt, Bibiana Onoa, Steven B. Smith, Ignacio Tinoco, Jr., and Carlos Bustamante
Science 27 April 2001: 733-737.
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Switching Repulsion to Attraction: Changing Responses to Slit During Transition in Mesoderm Migration

Sunita G. Kramer, Thomas Kidd, Julie H. Simpson, and Corey S. Goodman
Science 27 April 2001: 737-740.
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Differentiation of Embryonic Stem Cell Lines Generated from Adult Somatic Cells by Nuclear Transfer

Teruhiko Wakayama, Viviane Tabar, Ivan Rodriguez, Anthony C. F. Perry, Lorenz Studer, and Peter Mombaerts
Science 27 April 2001: 740-743.
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Molecular Analyses of Oral Polio Vaccine Samples

Hendrik Poinar, Melanie Kuch, and Svante Pääbo
Science 27 April 2001: 743-744.
Published online 25 April 2001 [DOI: 10.1126/science.1058463] (in Science Express Reports)
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Virus Maturation Involving Large Subunit Rotations and Local Refolding

J. F. Conway, W. R. Wikoff, N. Cheng, R. L. Duda, R. W. Hendrix, J. E. Johnson, and A. C. Steven
Science 27 April 2001: 744-748.
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Technical Comments

 Mechanisms Underlying Antigen-Specific CD8⁺ T Cell Homeostasis

Dominik Wodarz, Vladimir P. Badovinac, Amy R. Tvinnereim, Herbert W. Hethcote, and John T. Harty
Science 27 April 2001: 595.
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